Nokea
Regarding puberty:
- A. The beginning of puberty is closely related to bony changes rather than to age
- B. The first sign of puberty in a boy is the development of axillary hair
- C. Constitutional precocious puberty is commoner in girls than boys
- D. Delayed puberty is defined as lack of pubertal changes in a boy after 14 years of age
Correct Answer: C
Rationale: Constitutional precocious puberty is more common in girls than boys, often due to earlier activation of the hypothalamic-pituitary-gonadal axis.
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Which of the following conditions results primarily from mutation in the gene encoding Vitamin D receptor?
- A. Vitamin D dependent rickets type 1
- B. Vitamin D dependent rickets type 2
- C. X-linked hypophosphatemic rickets
- D. Autosomal dominant hypophosphatemic rickets
Correct Answer: B
Rationale: Vitamin D dependent rickets type 2 is caused by mutations in the vitamin D receptor gene, leading to resistance to vitamin D.
A feature of Turner syndrome is:
- A. Short stature
- B. Polydactyly
- C. Congenital heart defects
- D. Mental retardation
Correct Answer: A
Rationale: Short stature is a common feature of Turner syndrome, along with ovarian insufficiency and other physical abnormalities.
Which medication should the nurse give to a child diagnosed with transposition of the great vessels?
- A. Ibuprofen
- B. Betamethasone
- C. Prostaglandin E
- D. Indocin
Correct Answer: C
Rationale: Prostaglandin E keeps the ductus arteriosus open, which is essential for maintaining adequate circulation in transposition of the great vessels until corrective surgery is performed.
Mitochondrial DNA
- A. Has its own genome
- B. Is responsible for some forms of myopathies
- C. Can transmit diseases from parents to children
- D. Is present in neurons
Correct Answer: B
Rationale: Is responsible for some forms of myopathies
The nurse is caring for a child with Kawasaki disease (KD). A student nurse asks if there are medications to treat this disease. The nurse's response is:
- A. Immunoglobulin G and aspirin
- B. Immunoglobulin G and ACE inhibitors
- C. Immunoglobulin E and heparin
- D. Immunoglobulin E and ibuprofen
Correct Answer: A
Rationale: High-dose IV immunoglobulin G along with high-dose aspirin (salicylate therapy) is the current treatment for KD.