Strategies prescribers can use to prevent misuse of controlled prescription drugs include:
- A. Use of chemical dependency screening tools
- B. Firm limit-setting regarding prescribing controlled substances
- C. Practicing 'just say no' to deal with patients who are pushing the provider to prescribe controlled substances
- D. All of the above
Correct Answer: D
Rationale: All strategies "screening , limits , and refusal "help prevent misuse of controlled substances.
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NSAIDs combat fever by inhibiting which prostaglandin?
- A. Prostaglandin E2
- B. Prostaglandin I2
- C. Prostaglandin D2
- D. Prostaglandin F2
Correct Answer: A
Rationale: Prostaglandin E2 mediates fever in the hypothalamus; NSAIDs reduce fever by inhibiting its synthesis.
A nurse is teaching a client who has a new prescription for Brimonidine ophthalmic drops and wears soft contact lenses. Which of the following instructions should the nurse include in the teaching?
- A. This medication can stain your contacts.
- B. This medication can cause your pupils to constrict.
- C. This medication can absorb into your contacts.
- D. This medication can slow your heart rate.
Correct Answer: C
Rationale: Brimonidine can absorb into contacts , requiring removal before use to avoid irritation.
antagonist is a substance that:
- A. Binds to the receptors and initiates changes in cell function, producing maximal effect
- B. Binds to the receptors and initiates changes in cell function, producing submaximal effect
- C. Interacts with plasma proteins and doesn't produce any effect
- D. Binds to the receptors without directly altering their functions
Correct Answer: D
Rationale: An antagonist binds receptors without activating them, blocking agonist effects.
The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurse's best response?
- A. The doctor would have to complete a great deal of paperwork to get approval to prescribe that drug.
- B. Sometimes pharmaceutical companies are looking for volunteers to test a new drug and the doctor could give them your name.
- C. Drugs in the preclinical phase of testing are only tested on animals and so would not be available to you.
- D. Drugs in the preclinical phase of testing are given only to healthy young men and so would not be available to you.
Correct Answer: C
Rationale: During the preclinical phase of testing drugs are tested on animals and are not available to patients. In phase I, the drug is tested on volunteers who are usually healthy young men. It is only in phase III studies that the drug is made available to prescribers who agree to closely monitor patients getting the medication.
Milk and other foods that alkalinize the urine may:
- A. Result in basic drugs, being, reabsosibet in
- B. Increase the elimination of basic drugs in the urine
- C. Decrease the elimination of acidic drugs
- D. Not alter drug elimination due to the minimal change in urine pH
Correct Answer: C
Rationale: Alkalinizing urine increases ionization of acidic drugs, reducing their reabsorption and thus decreasing elimination.
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