Nokea
Substrate concentration & velocity curve indicates
- A. Michelis-Mentons equation
- B. Inverse relation
- C. Zero order kinetics
- D. All of the above
Correct Answer: C
Rationale: Substrate concentration vs. velocity in zero-order kinetics shows saturation, unlike first-order (Michaelis-Menten).
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The nurse is preparing to administer a medication from a multidose bottle. The label is torn and soiled but the name of the medication is still readable. What is the nurse's priority action?
- A. Discard the entire bottle and contents and obtain a new bottle.
- B. Find the drug information and create a new label for the bottle.
- C. Ask another nurse to verify the contents of the bottle.
- D. Administer the medication if the name of the drug can be clearly read.
Correct Answer: A
Rationale: When the drug label is soiled obscuring some information the safest action by the nurse is to discard the bottle and contents because drug labels contain a great deal of important information, far more than just the name of the drug. Concentration of the drug, expiration date, administration directions, and precautions may be missing from the label and so put the patient at risk. Looking up drug information in a drug handbook or consulting with another nurse will not supply the expiration date or concentration of medication. Be safe and discard the bottle and its contents.
Conjunctivitis in a child that is accompanied by acute otitis media is treated with:
- A. Sulfacetamide 10% ophthalmic solution (Bleph-10)
- B. Bacitracin/polymyxin B (Polysporin) ophthalmic drops
- C. Ciprofloxacin (Ciloxan) ophthalmic drops
- D. High-dose oral amoxicillin
Correct Answer: D
Rationale: Conjunctivitis with otitis suggests bacterial cause (e.g., H. influenzae), treated with oral amoxicillin.
Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.
Which of the following is considered a unit dose system?
- A. Floor stock bottle of aspirin 81 mg
- B. A prefilled Lovenox syringe
- C. One cartoon of Phenergan suppository
- D. Floor stock bottle of ibuprofen suspension
Correct Answer: B
Rationale: Examples of unit dose medications include a package that contains one tablet or capsule, a premeasured amount of a liquid drug, a prefilled syringe, or one suppository.
symptomatic and metabolic improvement. Until that time, which of the following might be administered adjunctively to suppress glucocorticoid synthesis?
- A. Cimetidine
- B. Cortisol (massive doses)
- C. Fludrocortisone
- D. Ketoconazole
Correct Answer: D
Rationale: Ketoconazole inhibits glucocorticoid synthesis by blocking adrenal steroidogenesis, useful in Cushing's syndrome management.