The bacterium Yersinia pestis is responsible for causing what disease?
- A. Tonsillitis
- B. Leprosy
- C. Plague
- D. Rat fever
Correct Answer: C
Rationale: The correct answer is C: Plague. Yersinia pestis is the bacterium responsible for causing the bubonic, septicemic, and pneumonic plague. The bacterium is transmitted to humans through infected flea bites or handling infected animals. Tonsillitis (A) is commonly caused by streptococcal bacteria, leprosy (B) is caused by Mycobacterium leprae, and rat fever (D) is another term for leptospirosis, caused by Leptospira bacteria.
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The causative agent of plague is:
- A. Bordetella pertussis
- B. Yersinia pestis
- C. Rickettsia prowazekii
- D. Treponema pallidum
Correct Answer: B
Rationale: The correct answer is B: Yersinia pestis. Y. pestis is the causative agent of plague, a serious infectious disease transmitted through fleas. It causes bubonic, pneumonic, and septicemic plague. Bordetella pertussis causes whooping cough, Rickettsia prowazekii causes epidemic typhus, and Treponema pallidum causes syphilis. Y. pestis is the correct answer because it is specifically associated with plague, making the other options incorrect.
Which of the following viruses could be reactivated under immunosuppressive therapy?
- A. Virus Parotitidis
- B. Rubella virus
- C. Influenza A
- D. None of the above
Correct Answer: D
Rationale: The correct answer is D, "None of the above," because viruses like Parotitidis (mumps), Rubella, and Influenza A are not typically associated with reactivation under immunosuppressive therapy. Reactivation is more commonly seen in latent viruses like herpesviruses (e.g., herpes simplex, varicella-zoster), cytomegalovirus, and Epstein-Barr virus. These viruses can remain dormant in the body and reactivate when the immune system is compromised. Therefore, the correct answer is D, as the viruses mentioned in choices A, B, and C do not fit the criteria for reactivation under immunosuppressive therapy.
Which of the following transport mechanisms transports water across the plasma membrane?
- A. osmosis
- B. facilitated diffusion
- C. phagocytosis
- D. exocytosis
Correct Answer: A
Rationale: Osmosis is the correct answer because it is the process by which water molecules move across a semi-permeable membrane from an area of low solute concentration to an area of high solute concentration. This movement occurs passively, driven by the concentration gradient. Facilitated diffusion (B) involves the transport of specific molecules with the help of carrier proteins, not water. Phagocytosis (C) is a process where cells engulf solid particles, not water molecules. Exocytosis (D) is the process of releasing substances from a cell by fusion of vesicles with the cell membrane, not the transport of water across the membrane.
In which of the following GIT infections, the bacteria adhere to the intestine wall and produce toxins
- A. Shigella spp.
- B. Salmonella spp.
- C. enterotoxigenic E. Coli (ETEC)
- D. Helicobacter pylori
Correct Answer: C
Rationale: The correct answer is C: enterotoxigenic E. Coli (ETEC). ETEC adheres to the intestine wall and produces toxins, leading to symptoms like diarrhea. Shigella spp. invade intestinal cells, Salmonella spp. cause inflammation, and Helicobacter pylori infects the stomach lining. This makes them incorrect choices for bacteria adhering to the intestine wall and producing toxins.
Which of the following stains is the most widely used differential stain in hematology laboratories?
- A. Carbolfuchsin stain
- B. Wright’s stain
- C. Ziehl-Neelson stain
- D. Kinyoun stain
Correct Answer: D
Rationale: The correct answer is D: Kinyoun stain. This stain is the most widely used differential stain in hematology labs because it is specifically designed for acid-fast bacteria like Mycobacterium tuberculosis. It differentiates these bacteria from others based on their cell wall composition. Carbolfuchsin stain (A) is used for acid-fast bacteria in microbiology. Wright's stain (B) is used for blood cell morphology. Ziehl-Neelsen stain (C) is also used for acid-fast bacteria but is less commonly used compared to Kinyoun stain in hematology labs.
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