Nokea
The client diagnosed with leukemia is scheduled for bone marrow transplantation. Which interventions should be implemented to prepare the client for this procedure? Select all that apply.
- A. Administer high-dose chemotherapy.
- B. Teach the client about autologous transfusions.
- C. Have the family members' HLA typed.
- D. Monitor the complete blood cell count daily.
- E. Provide central line care per protocol.
Correct Answer: A,C,D,E
Rationale: High-dose chemotherapy (A) ablates marrow, HLA typing (C) identifies donors, CBC monitoring (D) tracks counts, and central line care (E) prevents infection. Autologous transfusions (B) are irrelevant (donor marrow used).
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The client diagnosed with acute myeloid leukemia receives a bone marrow transplant. Which medication to prevent graft-versus-host disease (GVHD) should the nurse plan to administer?
- A. A cephalosporin antibiotic, such as ceftazidime
- B. An immunosuppressant, such as cyclosporine
- C. A chemotherapeutic agent, such as cisplatin
- D. Peginterferon alfa-2a for prevention and treatment of hepatitis
Correct Answer: B
Rationale: A. Antibiotics such as ceftazidime (Fortaz) are administered to prevent infection. B. GVHD occurs when the T lymphocytes proliferate from the transplanted donor marrow and mount an immune response against the recipient’s tissues. An immunosuppressant such as cyclosporine (Neoral) prevents the immune response. C. Cisplatin (Platinol AQ) is administered mainly to treat metastatic testicular, ovarian, and cervical carcinoma; advanced bladder cancer; and head and neck cancer. D. Interferons such as peginterferon alfa-2a (Pegasys) have antiviral activity, which decrease the progression of hepatic damage associated with hepatitis A and B. This would only be administered if the transplanted cells transmitted the disease. The biological agent interferon is used to treat follicular low-grade lymphomas.
The client is diagnosed with severe iron-deficiency anemia. Which statement is the scientific rationale regarding oral replacement therapy?
- A. Iron supplements are well tolerated without side effects.
- B. There is no benefit from oral preparations; the best route is IV.
- C. Oral iron preparations cause diarrhea if not taken with food.
- D. Very little of the iron supplement will be absorbed by the body.
Correct Answer: D
Rationale: Oral iron has low absorption (D), requiring high doses. Side effects (A) include GI upset, IV (B) is for severe cases, and diarrhea (C) is not primary (constipation is common).
The client is admitted with a diagnosis of colon cancer. Which finding in the client’s admission information should prompt the nurse to consider that the cancer may be located in the client’s descending colon?
- A. Pain in the lower abdomen
- B. Change in bowel habits
- C. Bright red blood in the stool
- D. Nausea and vomiting
Correct Answer: C
Rationale: A. Pain may be a symptom of a tumor located on the left side of the colon, but it is not exclusive and could be a symptom of a tumor elsewhere in the colon. B. Change of bowel habits may be a symptom of a tumor located on the left side of the colon, but this is not exclusive and could be a symptom of a tumor elsewhere in the colon. C. Bright red blood in the stool is a sign or symptom of a colorectal tumor located in the descending colon. D. Nausea and vomiting are not symptoms specific to colon cancer.
A client who receives a diagnosis of pernicious anemia asks why she must receive vitamin shots. What is the best answer for the nurse to give?
- A. Shots work faster than pills.'
- B. Your body cannot absorb vitamin B12 from foods.'
- C. Vitamins are necessary to make the blood cells.'
- D. You can get more vitamins in a shot than a pill.'
Correct Answer: B
Rationale: In pernicious anemia, the lack of intrinsic factor prevents absorption of vitamin B12 from foods, necessitating injections.
Which action should the nurse expect to perform after a client has a bone marrow biopsy taken from the iliac crest?
- A. Apply pressure to the site for one minute
- B. Administer a narcotic analgesic
- C. Apply an adhesive bandage to the site
- D. Place the client in a recumbent position
Correct Answer: C
Rationale: Applying an adhesive bandage to the site after a bone marrow biopsy prevents bleeding and protects the area. Pressure is typically applied for longer, narcotics are not routine, and recumbent positioning is not required.