2024 Nclex Questions Related

Review 2024 Nclex Questions related questions and content

The client is taking prednisone 7.5mg po each morning to treat his systemic lupus erythematosus. Which statement best explains the reason for taking the prednisone in the morning?

  • A. There is less chance of forgetting the medication if taken in the morning.
  • B. There will be less fluid retention if taken in the morning.
  • C. Prednisone is absorbed best with the breakfast meal.
  • D. Morning administration mimics the body's natural secretion of corticosteroid.
Correct Answer: D

Rationale: Taking corticosteroids in the morning mimics the body's natural release of cortisol, which follows a diurnal pattern with higher levels in the morning. This timing helps regulate the body's inflammatory response and minimizes potential side effects. Answer A is not the primary reason for morning dosing, as adherence concerns can be addressed through other means. Answer B is incorrect since fluid retention is not influenced by the timing of prednisone administration. Answer C is also incorrect as prednisone absorption is not significantly affected by whether it is taken with breakfast or not.