The physician orders tests to determine if a client has systemic lupus erythematosus (SLE). Which test result confirms SLE?
Correct Answer: B
Rationale: An above-normal anti-deoxyribonucleic acid (anti-dsDNA) test result confirms systemic lupus erythematosus (SLE). Anti-dsDNA antibodies are highly specific for SLE and are found in about 70% of individuals with the condition. These antibodies target the genetic material within the cell nucleus and are strongly associated with lupus nephritis, a severe complication of SLE. Therefore, an elevated anti-dsDNA test result would be a key indicator of SLE diagnosis.