NCLEX Pharmacology Cheat Sheet Related

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The client who has had a kidney transplant tells the nurse he has been taking St. John's wort, an herb, for depression. Which action should the nurse take first?

  • A. Praise the client for taking the initiative to treat the depression.
  • B. Remain nonjudgmental about the client's alternative treatments.
  • C. Refer the client to a psychologist for counseling for depression.
  • D. Instruct the client to quit taking the medication immediately.
Correct Answer: D

Rationale: St. John’s wort induces CYP3A4, reducing immunosuppressant efficacy (e.g., cyclosporine), risking transplant rejection. Stopping it is the priority.