The direct costs of drug therapy include:
- A. The actual cost of acquiring the medication
- B. The loss of income due to illness
- C. Pain and suffering due to inadequate drug therapy
- D. The cost of a funeral associated with premature death
Correct Answer: A
Rationale: Direct costs are the tangible expenses of acquiring the drug itself.
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A 20-year-old boy suffered from a moderate aspirin toxicity he may be managed by promoting its renal excretion when infused with:
- A. Ascorbid acid
- B. Ammonium chloride
- C. Arginine chloride
- D. Sodium bicarbonate
Correct Answer: D
Rationale: Sodium bicarbonate alkalinizes urine, enhancing aspirin (a weak acid) excretion.
Which of the following best describes the effect of propylthiouracil on thyroid hormone production?
- A. It blocks the release of thyrotropin-releasing hormone
- B. It inhibits uptake of iodide by thyroid cells
- C. It prevents the release of thyroid hormone from thyroglobulin
- D. It blocks iodination and coupling of tyrosines in thyroglobulin to form thyroid hormones
Correct Answer: D
Rationale: Propylthiouracil blocks iodination and coupling in thyroglobulin, inhibiting thyroid hormone synthesis.
Many patients self-medicate with antacids. Which patients should be counseled to not take calcium carbonate antacids without discussing it with their provider or a pharmacist first?
- A. Patients with kidney stones
- B. Pregnant patients
- C. Patients with heartburn
- D. Postmenopausal women
Correct Answer: A
Rationale: Calcium carbonate can worsen kidney stones; it's generally safe in pregnancy or heartburn without special caution.
Administration of exenatide is by subcutaneous injection:
- A. 30 minutes prior to the morning meal
- B. 60 minutes prior to the morning and evening meal
- C. 15 minutes after the evening meal
- D. 60 minutes before each meal daily
Correct Answer: B
Rationale: Exenatide is injected 60 minutes before morning and evening meals to optimize glucose control; timing is incorrect.
A nurse is teaching a patient about a new prescription for hydrochlorothiazide. Which statement indicates that the patient understands the teaching?
- A. I should increase my potassium intake.
- B. I may experience swelling in my legs.
- C. I need to monitor my blood sugar levels.
- D. I can take this medication any time of the day.
Correct Answer: A
Rationale: Hydrochlorothiazide can cause hypokalemia; increasing potassium intake shows understanding, unlike swelling (opposite effect) or timing flexibility (best in morning).
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