Nokea
The following drug may be used in the management of acromegaly:
- A. Leuprolide
- B. Octreotide
- C. Cosyntropin
- D. Desmopressin
Correct Answer: B
Rationale: Octreotide, a somatostatin analog, inhibits growth hormone in acromegaly.
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Which of the following two cyclooxygenase isoenzymes is constitutively expressed?
- A. COX-1
- B. COX-2
Correct Answer: A
Rationale: COX-1 is constitutively expressed in most tissues, maintaining normal functions, unlike inducible COX-2.
Precautions that should be taken when prescribing controlled substances include:
- A. Faxing the prescription for a Schedule II drug directly to the pharmacy
- B. Using tamper-proof paper for all prescriptions written for controlled drugs
- C. Keeping any pre-signed prescription pads in a locked drawer in the clinic
- D. Using only numbers to indicate the amount of drug to be prescribed
Correct Answer: B
Rationale: Tamper-proof paper prevents fraud, a key precaution; faxing Schedule II has restrictions, and locking pads or numbers-only are less specific.
The student nurses are learning to weigh patients and do vital signs. Weighing a client is a nursing intervention that is most important for what?
- A. Dosage calculation
- B. Assessing changes in fluid balance
- C. Assessing changes in nutritional status
- D. Caloric needs
Correct Answer: B
Rationale: Weighing assesses fluid balance changes, vital for adjusting drugs like diuretics in conditions such as CHF.
This graph shows the concentration-dependent effects of norepinephrine on arterial blood pressure, both alone, and in the presence of a fixed concentration of Drug X. Which type of antagonist is Drug X?
- A. Silent
- B. Non-competitive
- C. Competitive
- D. Chemical
Correct Answer: B
Rationale: A non-competitive antagonist reduces the maximal response without shifting the potency (EC50), as indicated by the answer key, likely showing a decreased maximum on the graph.
A thorough understanding of herbs is critical to patient safety. An example is the use of cinnamon to treat type II diabetes. It is important the patient uses Ceylon cinnamon, as the commercially available cassia cinnamon contains:
- A. Coumadin, which may lead to bleeding problems
- B. Coumarin, which can cause liver and kidney damage
- C. Cinnamic aldehyde, which is toxic to the kidney
- D. Cinnamate eugenol, which is toxic to the liver
Correct Answer: B
Rationale: Cassia cinnamon contains coumarin, which can be hepatotoxic and nephrotoxic in high doses.