The following drugs are contraindicated in renal failure:
- A. Nitrofurantoin
- B. Carbamazepine
- C. Salbutamol
- D. Metolazone
Correct Answer: A
Rationale: Nitrofurantoin is contraindicated in renal failure due to the risk of accumulation and subsequent toxicity, as the kidneys are unable to excrete the drug effectively.
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Arrhythmia in Children
- A. Re entry Tachycardia is the commonest
- B. Adenosine decreases the force of cardiac contractility
- C. SVT can cause hydrops foetalis
- D. Valsalva maneuver can restore sinus rhythm
Correct Answer: A
Rationale: Re-entry tachycardia is the most common type of arrhythmia in children.
All the following are true regarding coarctation of the aorta EXCEPT
- A. notching of ribs is noted
- B. doppler is useful for demonstrating severe obstruction
- C. diagnostic catheterization is mandatory before surgery
- D. CT and MRI are valuable noninvasive tools for evaluation when the echocardiogram is equivocal
Correct Answer: C
Rationale: Diagnostic catheterization is not always mandatory before surgery for coarctation of the aorta.
The following drugs induce hepatic enzymes:
- A. Rifampicin
- B. Phenobarbitone
- C. Cimetidine
- D. Erythromycin
Correct Answer: A
Rationale: Rifampicin is known to induce hepatic enzymes, which can increase the metabolism of other drugs and reduce their efficacy.
A child has an elevated antistreptolysin O (ASO) titer. Which combination of symptoms, in conjunction with this finding, would confirm a diagnosis of rheumatic fever?
- A. Subcutaneous nodules and fever
- B. Painful, tender joints, and carditis
- C. Erythema marginatum and arthralgia
- D. Chorea and elevated sedimentation rate
Correct Answer: B
Rationale: The presence of two major Jones criteria would indicate a high probability of rheumatic fever.
Polycythaemia:
- A. Is a common cause of jaundice in the newborn
- B. Is significant if haematocrit > 65% on a capillary sample
- C. May cause apnoeas
- D. Exchange transfusion is the treatment of choice in symptomatic cases
Correct Answer: B
Rationale: Polycythaemia is considered significant if the haematocrit exceeds 65% on a capillary sample, as it can lead to hyperviscosity and related complications.
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