The following drugs are excreted in the bile except:
- A. Erythromycin
- B. Novobiocin
- C. Chloramphenicol
- D. Rifampicin
Correct Answer: C
Rationale: Chloramphenicol is primarily excreted via the kidneys, not bile.
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A patient is ordered to receive a subcutaneous injection of heparin twice a day. When administering this drug to the patient, which of the following would be most important for the nurse to do to minimize tissue damage?
- A. Insert the needle at the appropriate angle.
- B. Select the needle length based on the patient's weight.
- C. Ensure that there is no hair on the injection site.
- D. Rotate the injection site regularly.
Correct Answer: D
Rationale: The nurse should rotate the injection sites to minimize the damage caused to the tissue. Inserting the needle at the proper angle and selecting the needle length based on the patient's weight will not significantly help in minimizing tissue damage if the same site is repeatedly injected. It is not necessary to avoid injection sites that have hair as long as the drug is administered in the upper arms, the upper abdomen, and the upper back.
Harold, a 42-year-old African American, has moderate persistent asthma. Which of the following asthma medications should be used cautiously, if at all?
- A. Betamethasone, an inhaled corticosteroid
- B. Salmeterol, an inhaled long-acting beta-agonist
- C. Albuterol, a short-acting beta-agonist
- D. Montelukast, a leukotriene modifier
Correct Answer: B
Rationale: Salmeterol carries a Black Box Warning for increased asthma-related deaths, especially in African Americans, requiring caution; others are safer.
Which antiarrhythmic medication is primarily used for atrial fibrillation?
- A. Propranolol
- B. Amiodarone
- C. Digoxin
- D. Verapamil
Correct Answer: B
Rationale: Amiodarone is widely used for atrial fibrillation due to its broad-spectrum antiarrhythmic effects across multiple classes.
Effects of glucagon are:
- A. Positive inotropic and chronotropic effects
- B. Negative inotropic and chronotropic effects
- C. Inhibition of Gs protein and decrease of CAMP
- D. Activation of Gq and accumulation of Inositol triphosphate
Correct Answer: A
Rationale: Glucagon has positive inotropic and chronotropic effects on the heart, increasing contractility and rate.
Jim is having a hip replacement surgery and would like to self-donate blood for the surgery. In addition to being prescribed epogen alpha he should also be prescribed:
- A. Folic acid to prevent megaloblastic anemia
- B. Iron, to start when the epogen starts
- C. An antihypertensive to counter the adverse effects of epogen
- D. Vitamin B12 to prevent pernicious anemia
Correct Answer: B
Rationale: Iron supports erythropoiesis with epoetin alfa; antihypertensives manage side effects, not prophylaxis.