The following factors trigger renin secretion:
- A. Hyponatremia
- B. ACTH
- C. Hypovolemia
- D. ADH
Correct Answer: C
Rationale: Hypovolemia: Renin is secreted by the kidneys in response to low blood volume (hypovolemia), initiating the renin-angiotensin-aldosterone system to conserve sodium and increase blood pressure.
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Which of the following is correct in breast milk jaundice?
- A. Peaks at first week of life
- B. Recurs with resumption of breast milk after trial stoppage
- C. Kernicterus can occur
- D. Seen in up to 10% of infants
Correct Answer: B
Rationale: Breast milk jaundice recurs when breastfeeding is resumed after a temporary stoppage.
The following diseases have diagnostic EEG findings:
- A. Petit mal epilepsy
- B. Infantile spasms
- C. Acute measles encephalopathy
- D. Herpes encephalitis
Correct Answer: B
Rationale: Infantile spasms, also known as West syndrome, have a characteristic EEG pattern called hypsarrhythmia, which is diagnostic.
Specific receptor defects occur in:
- A. Guillain-Barre syndrome
- B. Myasthenia gravis
- C. Graves' disease
- D. Ulcerative colitis
Correct Answer: B
Rationale: Myasthenia gravis is characterized by antibodies against acetylcholine receptors at the neuromuscular junction, leading to muscle weakness.
The following syndromes are caused by chromosomal abnormalities:
- A. Cri-du-chat syndrome
- B. Kearns-Sayre syndrome
- C. Marfan's syndrome
- D. Turner's syndrome
Correct Answer: D
Rationale: Turner's syndrome: Turner's syndrome is caused by a monosomy of the X chromosome, characterized by short stature, infertility, and heart defects.
A previously well 3½-month-old presents with poor feeding, diaphoresis during feeding, and poor growth. Vital signs reveal respirations of 70, pulse of 175, and blood pressure of 90/65 mm Hg in the upper and lower extremities. The cardiac examination reveals a palpable parasternal lift and a systolic thrill. A grade 4 holosystolic murmur and a mid-diastolic rumble are noted. The chest radiograph reveals cardiomegaly. The most likely diagnosis is
- A. cardiomyopathy
- B. myocarditis
- C. VSD
- D. coarctation of the aorta
Correct Answer: C
Rationale: The presentation suggests a large ventricular septal defect (VSD) causing significant left-to-right shunting and heart failure.