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The healthcare provider prescribes ganciclovir 375 mg intravenously (IV) every 12 hours to infuse over 90 minutes. The pharmacy delivers ganciclovir 375 mg in a 150 mL IV bag. How many mL/hour should the nurse program the infusion pump? (Enter a whole number only.)
Correct Answer: 100
Rationale: Infusion rate = 150 mL / (90 / 60) hours = 100 mL/hour.
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The healthcare provider prescribes magnesium hydroxide 4800 mg by mouth at bedtime for a client with constipation. The bottle is labeled 'Magnesium Hydroxide Saline Laxative, USP 400 mg per 5 mL.' How many ounces should the nurse instruct the client to take with each dose? (Enter numerical value only.)
Correct Answer: 0.41
Rationale: Volume: 4800 mg / (400 mg / 5 mL) = 12 mL. Convert to ounces: 12 × 0.033814 = 0.405768 oz, rounded to 0.41 oz.
A child who weighs 42 kg receives a prescription for methylprednisolone succinate 1.5 mg/kg/day intravenously in divided doses every 6 hours. The medication is available in 40 mg/mL vials. How many mL should the nurse administer with each dose? (Enter numerical value only. If rounding is required, round to the nearest tenth.)
Correct Answer: 0.4
Rationale: Daily dose: 1.5 mg/kg/day × 42 = 63 mg/day. Per dose (every 6 hours, 4 doses/day): 63 / 4 = 15.75 mg. Volume: 15.75 / 40 = 0.39375 mL, rounded to 0.4 mL.
The healthcare provider prescribes 1 liter of lactate Ringers to infuse in 8 hours. The IV administration set delivers 15 gtt/mL. How many mL/hour should the nurse program the infusion pump? (Enter numeric value only. If rounding is required, round to the nearest whole number.)
Correct Answer: 125
Rationale: Infusion rate = 1000 mL / 8 hours = 125 mL/hour.
The healthcare provider prescribes cefazolin 800 mg IM every six hours. The available vial is labeled, 'Cefazolin 1 gram,' and the instructions for reconstitution state, For IM use add 2.5 mL sterile water for injection to provide a total volume of 3.0 mL'. After reconstitution, the solution contains how many mg/mL? (Enter numeric value only. If rounding is required, round to the nearest whole number.)
Correct Answer: 333
Rationale: Concentration: 1000 mg / 3 mL = 333.333 mg/mL, rounded to 333.
A client receives a prescription for 1 liter of lactated Ringer's intravenously (IV) to be infused over 12 hours. The IV administration set delivers 60 gtt/mL. How many gtt/min should the nurse regulate the infusion? (Enter numerical value only. If rounding is required, round to the nearest whole number.)
Correct Answer: 83
Rationale: Volume = 1000 mL, drop factor = 60 gtt/mL, time = 12 hours = 720 minutes. Flow rate = (1000 × 60) / 720 = 83.333 gtt/min, rounded to 83.