The most rapid rate of drug absorption is achieved by __________ administration.
- A. on the skin
- B. intravenous
- C. intramuscular
- D. sublingual
Correct Answer: B
Rationale: The correct answer is B: intravenous administration. This route bypasses the first-pass metabolism, allowing the drug to directly enter the bloodstream for immediate distribution. In contrast, on the skin (A) and sublingual (D) routes have slower absorption rates due to barriers like skin layers or mucous membranes. Intramuscular (C) absorption is slower than intravenous due to slower perfusion rates in muscle tissues. Overall, intravenous administration provides the fastest and most direct route for drug absorption, making it the most rapid method.
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The immunity in syphilis is:
- A. Nonsterile (infectious)
- B. Antitoxic
- C. Humoral
- D. A + B + C
Correct Answer: A
Rationale: The correct answer is A because immunity in syphilis is nonsterile, meaning that individuals who have been infected may still carry the bacteria and be capable of transmitting the disease. This is due to the ability of the bacterium causing syphilis, Treponema pallidum, to evade the immune system by hiding within host cells.
Option B, antitoxic, is incorrect because syphilis is not caused by a toxin produced by the bacteria, but rather by the bacterium itself.
Option C, humoral, is also incorrect as syphilis immunity involves both humoral (antibody-mediated) and cell-mediated immune responses, not solely humoral immunity.
Option D is incorrect as it includes all three options, whereas in reality, the immunity in syphilis is primarily nonsterile.
The basic method for routine mumps diagnosis is;
- A. PCR
- B. Isolation on cell cultures
- C. ELISA
- D. Immunofluorescence method
Correct Answer: B
Rationale: The correct answer is B: Isolation on cell cultures. This method is the gold standard for routine mumps diagnosis as it involves isolating the virus in cell cultures to confirm the presence of the mumps virus. PCR (choice A) is used for detecting viral RNA, not for routine diagnosis. ELISA (choice C) detects antibodies, not the virus itself. Immunofluorescence method (choice D) is used for visualizing viral antigens but is not as reliable as isolating the virus in cell cultures for diagnosis.
Autoclaving will usually destroy/inactivate all fungi, bacteria, viruses, and most bacterial spores but will not necessarily eliminate
- A. neurotoxins.
- B. prions.
- C. protozoan cysts.
- D. mycoplasmas.
Correct Answer: B
Rationale: The correct answer is B: prions. Autoclaving, a method of sterilization using high pressure and steam, is effective at destroying most microorganisms including fungi, bacteria, viruses, and most bacterial spores due to denaturation of their proteins and nucleic acids. However, prions are highly resistant infectious proteins that are not easily eliminated by autoclaving. Prions can withstand high temperatures and pressure, making them a challenge to eradicate. Neurotoxins (A), protozoan cysts (C), and mycoplasmas (D) are susceptible to autoclaving and would be destroyed during the process.
Bacteria that use organic compounds as the source of both carbon and energy are referred to as:
- A. photoautotrophs
- B. chemoautotrophs
- C. photoheterotrophs
- D. chemoheterotrophs
Correct Answer: D
Rationale: The correct answer is D: chemoheterotrophs. Chemoheterotrophs use organic compounds as both their carbon source and energy source. They obtain energy by breaking down organic molecules through cellular respiration. Photoautotrophs (A) use light energy to produce organic compounds, chemoautotrophs (B) use inorganic compounds for energy, and photoheterotrophs (C) use light energy but require organic compounds as a carbon source. Therefore, chemoheterotrophs best describe bacteria that obtain both carbon and energy from organic compounds.
An etiological cause of hospital-acquired infections could be
- A. an opportunistic microorganism
- B. an obligate pathogen
- C. an obligate pathogenic bacterium or virus
- D. all are correct
Correct Answer: D
Rationale: The correct answer is D because hospital-acquired infections can be caused by a variety of microorganisms, including opportunistic pathogens and obligate pathogens such as bacteria or viruses. Opportunistic microorganisms take advantage of weakened immune systems in hospital patients, while obligate pathogens are capable of causing infections in healthy individuals. Therefore, all the choices are correct in this context as they represent potential etiological causes of hospital-acquired infections.