Care Hope College RN HESI Pharmacology Related

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The nurse administers naloxone to a patient with opioid-induced respiratory depression. An hour later, the nurse finds the patient has a respiratory rate of 4 breaths/minute, oxygen saturation of 75%, and is unresponsive. What action should the nurse take?

  • A. Administer a second dose of naloxone.
  • B. Prepare to assist with chest tube insertion.
  • C. Determine Glasgow Coma Scale score.
  • D. Initiate cardiopulmonary resuscitation (CPR).
Correct Answer: D

Rationale: Severe respiratory depression (4 breaths/min), hypoxia (75% SpO₂), and unresponsiveness require immediate CPR (D) to restore circulation/oxygenation. A second naloxone dose (A) may be needed but is secondary. Chest tubes (B) are irrelevant. Glasgow scoring (C) delays critical intervention.