The nurse is applying topical collagenase to a client. The nurse would assess the client for which of the following as a possible adverse reaction? Select all that apply.
- A. Mild pain
- B. Urticaria
- C. Numbness
- D. Pruritus
- E. Dermatitis
Correct Answer: A,C,E
Rationale: Possible adverse reactions associated with the topical administration of collagenase (Santyl) include mild, transient pain; possible numbness; and dermatitis.
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A nurse is instructing a client about how to apply the topical medication prescribed. Which of the following would the nurse identify as an appropriate way to remove the drug from the container? Select all that apply.
- A. Finger cot
- B. Clean finger
- C. Tongue blade
- D. Gauze pad
- E. Cotton swab
Correct Answer: A,C,D,E
Rationale: Using a finger cot, tongue blade, gauze pad, or cotton swab ensures hygienic application of the topical medication, minimizing contamination and direct skin contact.
A client is prescribed a topical corticosteroid. Which of the following would be appropriate for the nurse to do?
- A. Clean the area with an antiseptic before applying the drug.
- B. Apply the topical corticosteroid sparingly.
- C. Place a sterile cloth over the area of application.
- D. Rub the application into the skin vigorously.
Correct Answer: B
Rationale: Topical corticosteroids should be applied sparingly to minimize systemic absorption and adverse effects. Cleaning with an antiseptic may not be necessary unless directed, and a sterile cloth or vigorous rubbing is not typically recommended.
The nurse might suspect a hypersensitivity reaction has occurred in a client using azelaic acid (Azelex) if the client experiences a combination of which of the following? Select all that apply.
- A. Pruritus
- B. Urticaria
- C. Vomiting
- D. Erythema
- E. Mental status changes
Correct Answer: A,B,D
Rationale: Topical anti-infectives, like azelaic acid (Azelex), result in a rash, pruritus, urticaria, dermatitis, irritation, and erythema, which may indicate a hypersensitivity reaction to the drug.
A nursing instructor is evaluating the students' understanding of topical anti-infectives. The instructor determines that the group understands the information when they pair which drug with the infection treated correctly? Select all that apply.
- A. Erythromycin (Erygel) - acne vulgaris
- B. Ketoconazole (Nizoral) - episodes of HSV
- C. Ciclopirox (Loprox) - tinea pedis
- D. Acyclovir (Zovirax) - episodes of HSV
- E. Bacitracin (Baci-Rx) - tinea corporis
Correct Answer: A,C,D
Rationale: The following topical anti-infective drugs are matched correctly with the infection they treat: erythromycin (Erygel) - acne vulgaris; ciclopirox (Loprox) - tinea pedis; and acyclovir (Zovirax) - episodes of HSV.
A nurse is providing care to two clients, one with a Staphylococcus aureus skin infection and another with a Streptococcus pyogenes infection. Which of the following would the nurse expect the primary health care provider to prescribe? Select all that apply.
- A. Mupirocin (Bactroban)
- B. Acyclovir (Zovirax)
- C. Ketoconazole (Nizoral)
- D. Metronidazole (Metro-Gel)
- E. Retapamulin (Altabax)
Correct Answer: A,E
Rationale: Mupirocin (Bactroban) and retapamulin (Altabax) are topical anti-infectives that can be used to treat Staphylococcus aureus and Streptococcus pyogenes infections of the skin.
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