Timby's Introductory Medical-Surgical Nursing Thirteenth, North American Edition - Caring for Clients With Mood Disorders Related

Review Timby's Introductory Medical-Surgical Nursing Thirteenth, North American Edition - Caring for Clients With Mood Disorders related questions and content

The nurse is caring for a client who is receiving valproic acid. What clinical manifestation should the nurse periodically monitor for?

  • A. Hepatotoxicity
  • B. Hypertensive crisis
  • C. Orthostatic hypotension
  • D. Hyper alertness
Correct Answer: A

Rationale: The nurse should closely monitor a client on valproic acid, Depakote or Depakene, for hepatotoxicity. Frequent liver function tests and serum ammonia concentrations may be ordered. When a monoamine oxidase inhibitor is mixed with foods containing tyramine, clients are likely to develop a potentially fatal hypertensive crisis, not when taking valproic acid. Risk for orthostatic hypotension from psychotropic drugs is increased in older adults because of decreased functioning of the blood pressure-regulating mechanism. Some clients administered valproic acid experience sedation and ataxia.