NCLEX Trainer Test 4 Related

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The nurse is caring for a client with a history of bipolar disorder who is receiving valproic acid (Depakote) 500 mg PO bid. Which of the following laboratory results would be of GREATest concern to the nurse?

  • A. Liver enzymes elevated to twice normal.
  • B. Sodium 140 mEq/L.
  • C. Potassium 4.0 mEq/L.
  • D. Hemoglobin 13 g/dL.
Correct Answer: A

Rationale: Elevated liver enzymes suggest hepatotoxicity, a serious side effect of valproic acid, requiring immediate evaluation to prevent liver failure. Options B, C, and D are normal: sodium 140 mEq/L, potassium 4.0 mEq/L, and hemoglobin 13 g/dL do not indicate complications.