Drug Classifications and Illicit Drug Quiz Related

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The nurse is caring for a patient who had a severe, acute, previously unseen adverse effect of a drug in Phase III testing. The patient asks, After all the testing done on this drug, didnt they know this adverse effect could occur? What is the nurses best response? (Select all that apply.)

  • A. Phase III testing involves wide-scale population testing, which can reveal rare adverse effects not seen in earlier phases.
  • B. New adverse effects can lead to further study or withdrawal of the drug.
  • C. Phase I testing on healthy volunteers ensures all adverse effects are identified before patient use.
  • D. Even with extensive testing, some adverse effects may only appear after widespread use.
Correct Answer: C

Rationale: Phase III testing involves a large population, uncovering rare effects . Preclinical animal studies don't fully predict human responses (B is false). Phase I uses healthy volunteers, missing disease-specific effects (C is false). Rare effects emerge post-approval , potentially leading to further action .