Lewis's Medical Surgical Nursing in Canada, 5th Edition - Altered Immune Response and Transplantation Related

Review Lewis's Medical Surgical Nursing in Canada, 5th Edition - Altered Immune Response and Transplantation related questions and content

The nurse is caring for a patient who has experienced Goodpasture's syndrome. Which of the following adverse effects should the nurse be aware of?

  • A. Thrombocytopenia
  • B. Leukopenia
  • C. Angioedema
  • D. Pulmonary hemorrhage
Correct Answer: D

Rationale: Goodpasture's syndrome is a rare disorder involving the lungs and the kidneys. An antibody-mediated autoimmune reaction occurs involving the glomerular and alveolar basement membranes. The circulating antibodies combine with tissue antigen to activate the complement system which causes deposits of IgG to form along the basement membranes of the lungs or the kidneys. This reaction may result in pulmonary hemorrhage and glomerulonephritis.