Pharmacological and Parenteral Therapies NCLEX Questions Related

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The nurse is concerned that the adolescent may be developing a side effect of methotrexate. Which test or exam results should the nurse review prior to administration?

  • A. Folic acid level
  • B. Serum electrolytes
  • C. Complete blood count
  • D. Activated partial prothrombin time
Correct Answer: C

Rationale: A: Although methotrexate is a folic acid antagonist, it does not alter serum levels. B: Methotrexate has no effect on electrolytes. C: An adverse effect of methotrexate (Trexall) is aplastic anemia; thus, the nurse should review the CBC results before administration. D: Methotrexate has no effect on coagulation.