Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Assessment and Management of Patients with Endocrine Disorders Related

Review Brunner & Suddarth's Textbook of Medical-Surgical Nursing 14e (Hinkle 2017) - Assessment and Management of Patients with Endocrine Disorders related questions and content

The nurse is providing care for an older adult patient whose current medication regimen includes levothyroxine (Synthroid). As a result, the nurse should be aware of the heightened risk of adverse effects when administering an IV dose of what medication?

  • A. A fluoroquinalone antibiotic
  • B. A loop diuretic
  • C. A proton pump inhibitor (PPI)
  • D. A benzodiazepine
Correct Answer: D

Rationale: Oral thyroid hormones interact with many other medications. Even in small IV doses, hypnotic and sedative agents may induce profound somnolence, lasting far longer than anticipated and leading to narcosis (stupor like condition). Furthermore, they are likely to cause respiratory depression, which can easily be fatal because of decreased respiratory reserve and alveolar hypoventilation. Antibiotics, PPIs and diuretics do not cause the same risk.