Timby's Introductory Medical-Surgical Nursing Thirteenth, North American Edition - Caring for Clients With Dementia and Thought Disorders Related

Review Timby's Introductory Medical-Surgical Nursing Thirteenth, North American Edition - Caring for Clients With Dementia and Thought Disorders related questions and content

The nurse is relating medication classifications for Alzheimer type dementia to the pathophysiology of the disease process. Which neurotransmitter do most the medications on the market currently impact?

  • A. Dopamine
  • B. Acetylcholine
  • C. Norepinephrine
  • D. Epinephrine
Correct Answer: B

Rationale: Current drugs approved for treatment of dementia of the Alzheimer type include cholinesterase inhibitors, which increase acetylcholine by inhibiting cholinesterase, the enzyme that degrades it. When these drugs, tacrine (Cognex), donepezil (Aricept), or rivastigmine (Exelon), are administered in the early to middle stages of Alzheimer disease, some clients improve. Only memantine (Namenda) has a different mechanism of action.