Nokea
The nurse is teaching a group in the community about drug abuse. Which statement by the nurse is correct?
- A. Cue-induced cravings eventually disappear after long periods of abstinence by the person addicted to drugs
- B. Drug abuse and drug addiction are synonymous terms, describing dependence on drugs
- C. Drug addiction is characterized by emotional, mental, and sometimes physical dependence
- D. Drug addiction occurs when physical dependence is present
Correct Answer: C
Rationale: Addiction involves emotional/mental dependence, with physical optional; cravings persist, and abuse differs from addiction. Drug addiction occurs when emotional and mental dependence on a drug are present.
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A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
- A. Ensure the patient will not have increased adverse effects from the tamoxifen
- B. Identify if the patient is a poor metabolizer, potentially reducing conversion to active metabolites
- C. Evaluate risk of drug interactions with tamoxifen
- D. Determine if the patient requires a higher dose due to ultra-rapid metabolism
Correct Answer: B
Rationale: CYP2D6 testing identifies poor metabolizers who may not convert tamoxifen to its active form (endoxifen), impacting efficacy, not just ADRs or interactions .
A nurse has administered an opioid drug to a patient. Which action would be most appropriate for the nurse to do immediately after administering the drug?
- A. Monitoring the vital signs of the patient
- B. Documenting administration of the drug
- C. Informing the patient about the type of drug
- D. Updating the physician regarding the patient's condition
Correct Answer: B
Rationale: After administration of any drug, the nurse should immediately document the administration. After the documentation is complete, the nurse can record the patient's vital signs. The patient needs to be informed about the drug before the administration. The physician need not be immediately informed, unless the client develops severe adverse reactions.
What is correct concerning TI:
- A. A safer drug has a higher theraputic index
- B. TI might be equal to 1
- C. The more the unwanted adverse effect, the ration decreases
- D. You are in danger if you take 1.8 ng/ml of Digoxin which has the margin of safety (0.8-2)
Correct Answer: A
Rationale: A higher therapeutic index indicates a greater margin of safety between therapeutic and toxic doses, making the drug safer.
A nurse is teaching a patient about a new prescription for hydrochlorothiazide. Which statement indicates that the patient understands the teaching?
- A. I should increase my potassium intake.
- B. I may experience swelling in my legs.
- C. I need to monitor my blood sugar levels.
- D. I can take this medication any time of the day.
Correct Answer: A
Rationale: Hydrochlorothiazide can cause hypokalemia; increasing potassium intake shows understanding, unlike swelling (opposite effect) or timing flexibility (best in morning).
Nicotinic receptors are seen in
- A. Skeletal muscle
- B. Visceral smooth muscle
- C. Cardiac muscle
- D. Salivary glands
Correct Answer: A
Rationale: Nicotinic receptors are primarily at skeletal muscle neuromuscular junctions.