Physiological Adaptation NCLEX PN Questions Related

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The nurse should make which of the following responses when questioned by a client about the role of leptin in the body?

  • A. It increases food intake in clients, thereby promoting obesity.
  • B. It assists in the regulation of steroids.
  • C. It increases the total fat mass of people who are obese.
  • D. It might decrease the total fat mass in the bodies of people who are obese.
Correct Answer: D

Rationale: Leptin (recessive obesity gene-protein hormone) is expressed in fat cell coding for the protein that reacts to the percentage of fat cells in the body. Leptin is associated with increased energy expenditure and decreased food intake via hypothalamic control. Obese clients might have insensitivity or resistance to the effects of leptin. Leptin can affect other body hormones such as insulin. Genetic factors include leptin, uncoupling proteins, and the amount of brown/white fat in the body.