Nokea
The patient experiences a headache and is unable to move the left side of his body. The most likely cause is
- A. embolic stroke
- B. cerebral thrombosis
- C. cerebral abscess
- D. moyamoya disease
Correct Answer: A
Rationale: Embolic stroke is a common complication of cyanotic congenital heart disease.
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In truncus arteriosus, all the following are true EXCEPT
- A. VSD is always present
- B. clinical manifestations are characterized by severe cyanosis and the degree of cyanosis are high
- C. both ventricles fail clinically
- D. cyanosis is usually mild
Correct Answer: B
Rationale: Cyanosis is usually mild initially in truncus arteriosus.
Regarding cystic fibrosis:
- A. It is inherited as autosomal recessive
- B. There is increased risk of bronchial carcinoma in late adulthood
- C. Biliary cirrhosis is a recognised feature
- D. In neonates, intestinal obstruction may be the first presentation
Correct Answer: A
Rationale: Cystic fibrosis is an autosomal recessive disorder caused by mutations in the CFTR gene.
The jugular venous pressure (JVP) has a predictable relationship with pulmonary artery wedge pressure (PAWP). A JVP of >12 mm Hg predicted PAWP >22 mm Hg by 88% in which of the following trials?
- A. BNP
- B. ESCAPE
- C. EVEREST
- D. EMPA REG
Correct Answer: B
Rationale: The ESCAPE trial studied the effectiveness of therapies in patients with advanced heart failure and showed that elevated JVP was correlated with high pulmonary artery wedge pressures.
The Norwood procedure is used to correct:
- A. Transposition of the great vessels
- B. Hypoplastic left heart syndrome
- C. Tetralogy of Fallot (TOF)
- D. Patent ductus arteriosus (PDA)
Correct Answer: B
Rationale: The Norwood procedure is specifically performed for hypoplastic left heart syndrome.
Liver failure in children:
- A. Is always chronic in nature
- B. Wilson's disease is a common cause
- C. Leads to failure to thrive
- D. One of the causes is Reye syndrome
Correct Answer: D
Rationale: Reye syndrome is a known cause of acute liver failure in children, often associated with viral infections and aspirin use.