NCLEX RN Free Practice Questions Related

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The physician has prescribed Zyvox (linezolid) for a patient with VRE. The concurrent use of which medication may result in serotonin syndrome?

  • A. Nexium (esomeprazole)
  • B. Zoloft (sertraline)
  • C. Lipitor (atorvastatin)
  • D. Zyrtec (cetirizine)
Correct Answer: B

Rationale: Linezolid, a monoamine oxidase inhibitor, can cause serotonin syndrome when combined with SSRIs like Zoloft (sertraline), due to excessive serotonin accumulation. Nexium, Lipitor, and Zyrtec do not interact in this way.