NCLEX RN Medical Surgical Practice Questions Related

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The physician prescribes sulfasalazine (Azulfidine) for the client with ulcerative colitis to continue taking at home. Which instruction should the nurse give the client about taking this medication?

  • A. Avoid taking it with food.
  • B. Take the total dose at bedtime.
  • C. Take it with a full glass (240 mL) of water.
  • D. Stop taking it if urine turns orange-yellow.
Correct Answer: C

Rationale: Sulfasalazine should be taken with a full glass of water to ensure proper absorption and to prevent gastrointestinal irritation. It can be taken with food to reduce stomach upset, the dose is typically spread out during the day, and orange-yellow urine is a harmless side effect. CN: Pharmacological and parenteral therapies; CL: Synthesize