Practice NCLEX RN Test Related

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The RN on the oncology unit is preparing to mix and administer amphoteracin B (Fungizone) to a client. Which action is contraindicated for administering this drug IV?

  • A. Mix the drug with normal saline solution
  • B. Administer the drug over 4-6 hours
  • C. Hydrate with IV fluids 2 hours before the infusion
  • D. Premedicate the client - acetaminophen (Tylenol) and diphenhydramine (Benadryl)
Correct Answer: A

Rationale: Amphotericin B should not be mixed with normal saline due to precipitation risk; it requires dextrose solutions. Slow administration, hydration, and premedication are standard to reduce side effects.