Free NCLEX RN Exam Related

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The RN on the oncology unit is preparing to mix and administer amphoteracin B (Fungizone) to a client. Which action is contraindicated for administering this drug IV?

  • A. Mix the drug with normal saline solution.
  • B. Administer the drug over 4-6 hours.
  • C. Hydrate with IV fluids two hours before the infusion is scheduled to begin.
  • D. Premedicate the client with ordered acetaminophen (Tylenol) and diphenhydramine (Benadryl).
Correct Answer: A

Rationale: Amphotericin B should be mixed with D5W, not normal saline, due to stability issues. Slow infusion (B), hydration (C), and premedication (D) are standard practices.