Quizlet NCLEX PN 2023 Related

Review Quizlet NCLEX PN 2023 related questions and content

The test used to differentiate sickle cell trait from sickle cell disease is:

  • A. Sickle cell preparation.
  • B. Peripheral smear.
  • C. Sickledex.
  • D. Hemoglobin electrophoresis
Correct Answer: D

Rationale: The correct test to differentiate between sickle cell trait and sickle cell disease is hemoglobin electrophoresis. This test separates different types of hemoglobin based on their electrical charge, allowing for the identification of specific hemoglobin variants like HbS in sickle cell disease. Sickle cell preparation and Sickledex are not specific tests for this differentiation. While a peripheral smear can show sickle cells, it does not provide a definitive differentiation between the trait and the disease as it doesn't identify the specific hemoglobin variant present.