Nokea
There are several mechanisms through which AGEs can lead to increased oxidative stress. Question: Which AGE-induced mechanism supposedly plays an important role in the development of oxidative stress in endothelial cells?
- A. Crosslinking of matrix proteins
- B. Induction of apoptosis
- C. Intracellular glycation by methylglyoxal
- D. All three statements provided above are correct
Correct Answer: C
Rationale: AGEs spark stress methylglyoxal's indoor glycation fries cells, outpacing crosslinking or death calls. Key in endothelium, a chronic oxidative kick nurses target this mess.
You may also like to solve these questions
A client has a platelet count of 9800/mm^3. What action by the nurse is most appropriate?
- A. Assess the client for calf pain, warmth, and redness.
- B. Instruct the client to call for help to get out of bed.
- C. Obtain cultures as per the facility's standing policy.
- D. Place the client on protective isolation precautions.
Correct Answer: B
Rationale: A platelet count of 9800/mm^3 is severely low (normal is 150,000-450,000/mm^3), indicating thrombocytopenia, a common chemotherapy side effect that heightens bleeding risk. The most appropriate action is instructing the client to call for help before getting out of bed to prevent falls or injuries that could trigger uncontrolled bleeding, such as intracranial hemorrhage. Assessing for calf pain, warmth, and redness checks for thrombosis, which is unrelated to low platelets thrombosis risk rises with high counts. Obtaining cultures relates to infection, tied to low white cells, not platelets. Protective isolation is for neutropenia, not thrombocytopenia. This safety-focused intervention minimizes physical risk, crucial in oncology where low platelets demand proactive prevention to avoid life-threatening bleeds, empowering the client while ensuring nurse oversight.
A previously well 25 week pregnant lady presents as a neighbours child she was looking after 2 days ago has developed chicken pox. What would you advise?
- A. Check her serology
- B. Zoster immunoglobulin if negative serology
- C. Prophylactic aciclovir if negative serology
- D. A and B
Correct Answer: A
Rationale: Pregnant, 25 weeks check serology; VZIG or aciclovir jumps if negative, not all. Nurses test first, a chronic fetal guard.
The home health nurse is caring for a patient who has been receiving interferon therapy for treatment of cancer. Which statement by the patient indicates a need for further assessment?
- A. I have frequent muscle aches and pains.'
- B. I rarely have the energy to get out of bed.'
- C. I experience chills after I inject the interferon.'
- D. I take acetaminophen (Tylenol) every 4 hours.'
Correct Answer: B
Rationale: Interferon's flu-like hell aches , chills , and Tylenol use are par but crushing fatigue flags dose-limiting toxicity, hinting at overdose or depression. Nurses in oncology dig deeper here rarely out of bed' could mean more than side effects, needing med tweaks or psych consult, critical for home care balance.
Set in motion and continue the trajectory projection and scheme' is a goal of management in which of the following trajectory phases?
- A. Pretrajectory
- B. Onset
- C. Comeback
- D. Downward
Correct Answer: C
Rationale: Comeback phase kicks plans alive sustaining chronic care's path, not preventing, starting, or adapting decline. Nurses steer this, a rebound's drive.
Choose the CORRECT statement Babies born from mothers with gestational diabetes:
- A. Are at a high risk of being born with diabetes
- B. Are usually hypoglycaemic due to maternal insulin drug therapy
- C. Are usually of higher birth weight
- D. Are always given a glucose challenge test
Correct Answer: C
Rationale: Gestational diabetes fattens babies high maternal sugar pumps fetal growth, a hefty birth norm. They don't inherit diabetes at birth, hypo's rare unless mom's on insulin, tests aren't routine. Nurses track this, a chronic womb echo.