Roach's Introductory Clinical Pharmacology 11th Edition - Otic and Ophthalmic Preparations Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Otic and Ophthalmic Preparations related questions and content

Trifluridine is being administered to a patient who is being treated for epithelial keratitis. The nurse caring for this patient should know that which of the following is a local reaction to trifluridine?

  • A. Edema of the eyes
  • B. Loss of visual acuity
  • C. Cataract formation
  • D. Delayed wound healing
Correct Answer: A

Rationale: Trifluridine is an antiviral drug, and administration of antiviral ophthalmics may cause local reactions such as edema of the eyes or eyelids, irritation, pain, pruritus, inflammation, foreign body sensation, and corneal clouding. Loss of visual acuity, cataract formation, and delayed wound healing are the local adverse reactions associated with the administration of corticosteroid ophthalmic preparations like dexamethasone phosphate and are not related to the administration of trifluridine.