Tuberculine was injected intracutaneously to the child for tuberculin test. Marked hyperemia, tissue infiltration developed on the place of injection in 24 hours. What mechanism caused these modifications?
Correct Answer: C
Rationale: The correct answer is C: Granuloma formation. In response to tuberculosis antigen (tuberculin), the immune system forms a granuloma at the injection site as a defense mechanism. Granulomas are organized collections of immune cells that wall off the antigen and prevent its spread. This process involves macrophages, T cells, and fibroblasts.
Choice A (Cells cytotoxity) is incorrect because tuberculin test does not involve direct cell cytotoxicity. Choice B (Reagin type cytotoxity) is incorrect as reagin type hypersensitivity is associated with allergic reactions, not granuloma formation. Choice D (Immunocomplex cytotoxity) is also incorrect as immunocomplex cytotoxicity refers to tissue damage caused by immune complexes, not granuloma formation.
Nokea