Microbiology Chapter 10 Test Bank Related

Review Microbiology Chapter 10 Test Bank related questions and content

Tuberculine was injected intracutaneously to the child for tuberculin test. Marked hyperemia, tissue infiltration developed on the place of injection in 24 hours. What mechanism caused these modifications?

  • A. Cells cytotoxity
  • B. Reagin type cytotoxity
  • C. Granuloma formation
  • D. Immunocomplex cytotoxity
Correct Answer: C

Rationale: The correct answer is C: Granuloma formation. In response to tuberculosis antigen (tuberculin), the immune system forms a granuloma at the injection site as a defense mechanism. Granulomas are organized collections of immune cells that wall off the antigen and prevent its spread. This process involves macrophages, T cells, and fibroblasts.

Choice A (Cells cytotoxity) is incorrect because tuberculin test does not involve direct cell cytotoxicity. Choice B (Reagin type cytotoxity) is incorrect as reagin type hypersensitivity is associated with allergic reactions, not granuloma formation. Choice D (Immunocomplex cytotoxity) is also incorrect as immunocomplex cytotoxicity refers to tissue damage caused by immune complexes, not granuloma formation.