Roach's Introductory Clinical Pharmacology 11th Edition - Immunologic Agents Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Immunologic Agents related questions and content

Vaccines containing live organisms are not administered to clients taking which of the following drugs as insufficient numbers of antibodies are produced to prevent the disease because these drugs suppress the immune system? Select all that apply.

  • A. Methylprednisolone (Medrol)
  • B. Ciprofloxacin (Cipro)
  • C. Prednisolone (Orapred)
  • D. Paclitaxel (Taxol)
  • E. Vincristine (Oncovin)
Correct Answer: A,C,D,E

Rationale: Live vaccines are contraindicated with corticosteroids (methylprednisolone, prednisolone) and antineoplastic drugs (paclitaxel, vincristine) due to immune suppression.