Nokea
What clinical specimen can be analysed in the diagnosis of sexually transmitted infections:
- A. Genital ulcer secretion
- B. Lymph node punctate
- C. Serum
- D. All are correct
Correct Answer: D
Rationale: Certainly! The correct answer is D because all three options (A, B, and C) can be analyzed in the diagnosis of sexually transmitted infections. Genital ulcer secretions can reveal the presence of pathogens causing STIs, lymph node punctate can indicate systemic infection, and serum can be tested for specific STI antibodies. Therefore, all these clinical specimens are essential for a comprehensive diagnosis of sexually transmitted infections. The other choices (A, B, C) are incorrect as they individually represent important specimens used in the diagnosis process.
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The sample used to proving epidemic meningitis is:
- A. CSF transported at 37°C (CSF sample, blood, nasopharyngeal secretion)
- B. Feces
- C. CSF transported at +4°C
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A because CSF (Cerebrospinal fluid) is the sample used for proving epidemic meningitis. It should be transported at 37°C to maintain its integrity. Blood and nasopharyngeal secretions are not typically used for diagnosing meningitis. Choice B, feces, is unrelated to the diagnosis of meningitis. Choice C, CSF transported at +4°C, is incorrect as it should be transported at 37°C to prevent degradation of the sample. Therefore, A is the correct choice for proving epidemic meningitis due to the specificity of the sample and the proper transport conditions.
Comma-shaped rod, causes high volume watery diarrhea is:
- A. Campylobacter jejuni
- B. Vibrio cholerae
- C. Pseudomonas aeruginosa
- D. Proteus mirabilis
Correct Answer: B
Rationale: The correct answer is B: Vibrio cholerae. Vibrio cholerae is a comma-shaped rod bacterium that causes high volume watery diarrhea by producing cholera toxin. This toxin leads to the secretion of large amounts of fluid into the intestines. Campylobacter jejuni (A) typically causes bloody diarrhea. Pseudomonas aeruginosa (C) and Proteus mirabilis (D) are not associated with high volume watery diarrhea.
A 45-year-old patient complains of body temperature rise up to 40oC, general weakness, headache, painfulness and spastic muscle contractions around the wound in the shin. He received this wound 5 days ago when working in his garden. He requested no medical care back then. What wound infection can be suspected?
- A. Tetanus
- B. Anthrax
- C. Erysipelas
- D. Gram-positive
Correct Answer: A
Rationale: The correct answer is A: Tetanus. The patient's symptoms of muscle contractions, fever, and wound history suggest tetanus, caused by Clostridium tetani bacteria commonly found in soil. The spastic muscle contractions around the wound are classic for tetanus due to the neurotoxin produced by the bacteria. General weakness and headache are also common symptoms.
B: Anthrax is unlikely as it presents with different symptoms such as skin lesions, respiratory symptoms, and gastrointestinal symptoms.
C: Erysipelas is characterized by red, swollen patches on the skin, not consistent with the symptoms described.
D: Gram-positive is not a specific diagnosis but a broad category of bacteria. Tetanus is caused by Clostridium tetani, which is a Gram-positive bacterium, but this choice does not provide a specific infection diagnosis.
Which of the following bacteria produce a toxin that inhibits protein synthesis?
- A. Shigella dysenteriae
- B. Escherichia coli
- C. Clostridium tetani
- D. Staphylococcus aureus
Correct Answer: A
Rationale: The correct answer is A: Shigella dysenteriae. This bacterium produces Shiga toxin, which inhibits protein synthesis by inactivating the ribosomes. Shigella dysenteriae is known to cause severe gastrointestinal infections.
Choice B: Escherichia coli typically does not produce toxins that inhibit protein synthesis. E. coli strains may produce toxins that cause diarrhea.
Choice C: Clostridium tetani produces tetanospasmin toxin, which affects the nervous system but does not inhibit protein synthesis.
Choice D: Staphylococcus aureus produces toxins like enterotoxins and exotoxins but these toxins do not directly inhibit protein synthesis.
Rheumatic fever is usually a complication of a(n) __________ infection.
- A. Escherichia coli
- B. Streptococcus pyogenes
- C. Staphylococcus epidermidis
- D. Staphylococcus aureus
Correct Answer: B
Rationale: Rationale:
1. Streptococcus pyogenes is the causative agent of strep throat.
2. If untreated, strep throat can lead to rheumatic fever.
3. Rheumatic fever is an autoimmune complication of streptococcal infections.
4. E. coli, S. epidermidis, and S. aureus are not typically associated with rheumatic fever.