Nokea
What does affinity mean?
- A. The effective dose of a drug.
- B. A measure of how tightly a drug binds to a receptor.
- C. A measure of bioavailability of a drug.
- D. The dose range of a drug.
Correct Answer: B
Rationale: B' is correct because affinity in pharmacodynamics measures how tightly a drug binds to its receptor, influencing efficacy. 'A' and 'D' relate to dosing, not binding. 'C' is pharmacokinetics, not affinity. 'B' fits the receptor-ligand interaction model central to drug action studies.
You may also like to solve these questions
A common side effect of fibrates is:
- A. Myopathy
- B. Hyperglycemia
- C. Hypertension
- D. Hyperkalemia
Correct Answer: A
Rationale: A' is correct because myopathy (muscle pain) is a common fibrate side effect, especially with statins, per clinical data. 'B' (hyperglycemia), 'C' (hypertension), and 'D' (hyperkalemia) are rare. Myopathy risk necessitates monitoring.
A client is receiving a brand name drug and wants to change to the generic form because it is less expensive. What is the best outcome for this client?
- A. State two ways a brand name drug differs from a generic name drug.
- B. Take the brand name drug after speaking with the physician.
- C. Ask the nurse why brand name drugs are better than generic drugs.
- D. List two ways to obtain the medication at a reduced cost.
Correct Answer: A
Rationale: The best outcome is A: 'State two ways a brand name drug differs from a generic name drug.' Page 6 notes differences in bioavailability and inert ingredients, an educational goal. B, C, and D are less focused on understanding. The text supports A per the learning outcome on page 21.
When describing the various types of medications to a group of nursing students, a nursing instructor would identify which of the following as a source for deriving medications?
- A. Plants
- B. Synthetic sources
- C. Animals
- D. Minerals
Correct Answer: A
Rationale: Plants (A) are a key source, alongside synthetic sources (B), molds (C in original), minerals (D), and animals (E in original), per the text. All are valid, but A is selected as a primary example of natural derivation. The text lists these sources comprehensively, showing medications come from both nature and labs, with plants being a foundational source historically and currently.
The physician must keep which of the following records when using drugs found on the DEA list of scheduled medications?
- A. a log of all scheduled medications given
- B. copies of the supplier's invoices showing the receipt of the drug
- C. a copy of a BNDD number for each place where the physician administers Schedule II medications
- D. all of the above
Correct Answer: D
Rationale: All of the above' is correct because DEA regulations require physicians to maintain a log of scheduled medications administered (a), keep supplier invoices for receipt (b), and, though BNDD is outdated, modern equivalents like DEA registration numbers per location apply (c interpreted as DEA compliance). 'a' or 'b' alone misses other requirements, and 'c' as BNDD is a misnomer but contextually fits DEA rules. Comprehensive record-keeping prevents diversion, per Controlled Substances Act mandates.
Which of these statins is safe to consume with grapefruit juice?
- A. Rosuvastatin
- B. Atorvastatin
- C. Simvastatin
- D. Lovastatin
Correct Answer: A
Rationale: Rosuvastatin (Choice A) is minimally metabolized by CYP3A4, unaffected by grapefruit juice, making it correct. Atorvastatin (Choice B), simvastatin (Choice C), and lovastatin (Choice D) are CYP3A4 substrates, increasing levels with grapefruit, confirming A.