2024 PN NCLEX Questions Related

Review 2024 PN NCLEX Questions related questions and content

What effect can medication bound to protein have?

  • A. reduced drug availability
  • B. limited distribution of the drug to receptor sites
  • C. less availability to produce desired medicinal effects
  • D. decreased metabolism of the drug by the liver
Correct Answer: C

Rationale: Medication bound to protein leads to less availability to produce desired medicinal effects because only unbound drugs can interact with active receptor sites. If a drug is bound to protein, it cannot bind with a receptor site, reducing its effectiveness. Choice A is incorrect because binding to protein reduces drug availability. Choice B is incorrect because distribution to receptor sites is ineffective if the drug is bound to protein. Choice D is incorrect because metabolism does not occur until the drug is removed from the protein molecule by the liver, allowing the protein to return to circulation.