Free Pediatric CCRN Practice Questions Related

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What is an early clinical manifestation of bilirubin encephalopathy in the newborn?

  • A. Cognitive impairment
  • B. Absence of stooling
  • C. Lethargy or irritability
  • D. Increased or decreased temperature
Correct Answer: C

Rationale: An early clinical manifestation of bilirubin encephalopathy in a newborn is lethargy or irritability. Bilirubin encephalopathy, also known as kernicterus, is a serious condition that occurs when high levels of unconjugated bilirubin build up in the brain tissues. Initially, the baby may become lethargic or irritable due to the toxic effects of bilirubin on the central nervous system. As the condition progresses, symptoms may include poor feeding, high-pitched crying, muscle tone abnormalities, and eventually may lead to more severe consequences such as seizures and irreversible neurological damage. Prompt recognition and treatment of bilirubin encephalopathy are crucial to prevent long-term complications.