What is glucagon, where is it produced, and what is its function?
- A. Produced in the liver, releases glucose
- B. Produced in the pancreas, raises blood sugar
- C. Produced in the pancreas, lowers blood sugar
- D. Produced in the adrenal glands, regulates stress response
Correct Answer: B
Rationale: Glucagon is a hormone produced in the pancreas and functions to raise blood sugar levels. It does so by signaling the liver to release stored glucose into the bloodstream. Therefore, the correct answer is B, 'Produced in the pancreas, raises blood sugar.' Choices A, C, and D describe functions or locations of other hormones, not glucagon. Glucagon is specifically released by alpha cells in the pancreas, making option B the correct choice.
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Which of the following is directly transcribed from DNA and represents the first step in protein synthesis?
- A. siRNA
- B. rRNA
- C. mRNA
- D. tRNA
Correct Answer: C
Rationale: mRNA (messenger RNA) is directly transcribed from DNA in the nucleus during the process of transcription. It serves as a template for protein synthesis during translation in the cytoplasm. mRNA carries genetic information from the DNA to the ribosomes, where it determines the sequence of amino acids in a protein. Thus, mRNA represents the first step in protein synthesis as it carries the code from the DNA to be translated into a protein. Choice A, siRNA (small interfering RNA), is involved in post-transcriptional gene silencing and does not play a role in protein synthesis. Choice B, rRNA (ribosomal RNA), is a component of the ribosome and plays a structural and functional role in protein synthesis but is not directly transcribed from DNA. Choice D, tRNA (transfer RNA), is responsible for bringing amino acids to the ribosome during protein synthesis but is not directly transcribed from DNA.
Which type of capillary is the most permeable?
- A. Continuous capillaries
- B. Sinusoidal capillaries
- C. Fenestrated capillaries
- D. Vascular capillaries
Correct Answer: B
Rationale: Sinusoidal capillaries are indeed the most permeable type. They are characterized by large gaps between endothelial cells, allowing for the passage of large molecules and cells. These capillaries are commonly found in organs like the liver, bone marrow, and spleen where high permeability is required for specialized functions such as filtration and exchange of substances.
Continuous capillaries have tight junctions and are the least permeable, found in muscles, lungs, and the central nervous system where strict control over permeability is needed. Fenestrated capillaries, on the other hand, have small pores or fenestrations and are intermediate in permeability, found in organs like the kidneys, endocrine glands, and intestines where selective permeability is necessary. Vascular capillaries is not a specific type of capillary and is not a valid choice.
Which cells myelinate neurons in the CNS?
- A. Schwann cells
- B. Astrocytes
- C. Microglia
- D. Oligodendrocytes
Correct Answer: D
Rationale: The correct answer is D, Oligodendrocytes. Oligodendrocytes are responsible for myelinating neurons in the central nervous system (CNS). Schwann cells, found in the peripheral nervous system, are responsible for myelinating neurons there. Astrocytes support and maintain the neuronal environment, while microglia function as immune cells in the CNS, participating in immune responses and cellular debris clearance. Therefore, choices A, B, and C are incorrect for myelination of CNS neurons.
What is the bottom number in a blood pressure reading?
- A. Diastolic pressure
- B. Systolic pressure
- C. Pulse rate
- D. Mean arterial pressure
Correct Answer: A
Rationale: The correct answer is A: Diastolic pressure. The bottom number in a blood pressure reading represents the diastolic pressure, which indicates the lowest pressure in the arteries when the heart is resting between beats. This value is important in understanding the overall health of the cardiovascular system. Choice B, Systolic pressure, is the top number in a blood pressure reading and represents the pressure in the arteries when the heart is contracting. Choice C, Pulse rate, refers to the number of times the heart beats in a minute. Choice D, Mean arterial pressure, is a calculated value using both systolic and diastolic pressures to provide an average pressure in the arteries during a cardiac cycle, but it is not the bottom number in a blood pressure reading.
Which of the following are the abdominal quadrants?
- A. RUQ, RLQ, LLQ, LUQ
- B. RUQ, LUQ, RLQ, LLQ
- C. LUQ, RUQ, LLQ, RLQ
- D. LLQ, LUQ, RUQ, RLQ
Correct Answer: B
Rationale: The correct answer is B: RUQ, LUQ, RLQ, LLQ. The four abdominal quadrants are named as follows: Right Upper Quadrant (RUQ), Left Upper Quadrant (LUQ), Right Lower Quadrant (RLQ), and Left Lower Quadrant (LLQ). These quadrants are used in healthcare to describe specific areas of the abdomen during assessments and discussions related to abdominal anatomy and pathology. Choices A, C, and D are incorrect because they do not follow the standard order of the abdominal quadrants.