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What is the significance of studying pedigrees in human genetics?

  • A. Predicting the exact outcome of genetic crosses in humans.
  • B. Tracing the inheritance of complex traits with multiple contributing genes.
  • C. Identifying carriers of dominant genetic disorders.
  • D. Determining the risk of acquiring a specific mutation de novo.
Correct Answer: B

Rationale: Pedigrees are diagrams that show the relationships within a family and can be used to track the inheritance patterns of specific traits or diseases. While pedigrees can provide information on the inheritance of single gene disorders (such as identifying carriers of dominant genetic disorders, as mentioned in option C), their primary significance lies in studying complex traits with multiple contributing genes. These traits do not follow simple Mendelian inheritance patterns and are influenced by both genetic and environmental factors. By analyzing pedigrees, researchers can identify patterns of inheritance for complex traits, such as polygenic diseases or traits influenced by gene-environment interactions. Therefore, option B is the most appropriate choice as it captures the main significance of studying pedigrees in human genetics.