Nokea
What was the important contribution to microbiology of Anton Van Leeuwenhoek in the 1600s?
- A. He was the first to observe microorganisms
- B. He disproved the theory of spontaneous generation of microorganisms
- C. He was the first to show that a disease could be caused by a microorganism
- D. He was the first to describe the process of fermentation
Correct Answer: A
Rationale: The correct answer is A: He was the first to observe microorganisms. Van Leeuwenhoek's important contribution to microbiology was his discovery of microorganisms using his own handcrafted microscopes. This observation revolutionized the field by providing the first direct evidence of the existence of microorganisms.
Choice B is incorrect because Leeuwenhoek's observations actually supported the idea of spontaneous generation. Choice C is incorrect because he did not link microorganisms to diseases. Choice D is incorrect because the process of fermentation was described by others before Leeuwenhoek.
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Which of the following is NOT a common condition associated with Type I hypersensitivity?
- A. Asthma
- B. Food allergies
- C. Anaphylaxis
- D. Systemic lupus erythematosus (SLE)
Correct Answer: D
Rationale: The correct answer is D: Systemic lupus erythematosus (SLE). Type I hypersensitivity involves IgE-mediated reactions to allergens, leading to immediate responses like asthma, food allergies, and anaphylaxis. SLE is an autoimmune disease involving immune complexes and not IgE antibodies. Therefore, SLE is not directly associated with Type I hypersensitivity. Asthma, food allergies, and anaphylaxis are all examples of Type I hypersensitivity reactions due to IgE-mediated mechanisms.
Which of the following is an example of passive immunization?
- A. The protection against smallpox that is provided by inoculation with cowpox
- B. The rapid protection that is provided by the primary immune response to a vaccine
- C. The immune protection provided to an individual after receiving serum from someone previously exposed to a pathogen
- D. Immunization of a child under the supervision of a parent or guardian
Correct Answer: C
Rationale: Passive immunization involves the transfer of pre-formed antibodies to confer immediate protection. Choice C is correct as it describes receiving serum containing antibodies from an immune individual. Choice A is incorrect because it describes active immunization. Choice B is incorrect as it refers to the primary immune response, which is part of active immunization. Choice D is incorrect as it describes the process of immunization itself, not passive immunization.
What is a significant consequence of the evolutionary arms race between hosts and pathogens?
- A. Pathogens evolve slower than hosts
- B. Hosts develop epigenetic changes for immune adaptation
- C. Mutations in hosts always outpace pathogen evolution
- D. Hosts and pathogens remain static in their interactions
Correct Answer: B
Rationale: The correct answer is B because hosts developing epigenetic changes for immune adaptation is a significant consequence of the evolutionary arms race between hosts and pathogens. This adaptation allows hosts to better defend against evolving pathogens over time. This process is dynamic, as both hosts and pathogens continuously evolve in response to each other.
Choice A is incorrect because pathogens can evolve rapidly to adapt to host defenses. Choice C is incorrect because while hosts may have mutations that provide advantages, pathogens can also evolve to overcome host defenses. Choice D is incorrect as the interaction between hosts and pathogens is characterized by constant adaptation and change, not remaining static.
Priority Decision: On assessment of a central venous access device (CVAD) site, the nurse observes that the transparent dressing is loose along two sides. What should the nurse do immediately?
- A. Wait and change the dressing when it is due
- B. Tape the two loose sides down and document
- C. Apply a gauze dressing over the transparent dressing and tape securely
- D. Remove the dressing and apply a new transparent dressing using sterile technique
Correct Answer: D
Rationale: Loose dressings increase infection risk; replacing the dressing with sterile technique ensures safety.
Select the correct statement during an allergic reaction.
- A. An allergen binds with IgE antibodies.
- B. The mast cells are deactivated.
- C. The body is immunodeficient.
- D. Helper T cells release histamine.
Correct Answer: A
Rationale: Step-by-step rationale:
1. During an allergic reaction, allergens trigger the release of IgE antibodies.
2. The allergen binds with IgE antibodies, leading to the activation of mast cells.
3. Activated mast cells release histamine and other inflammatory mediators.
4. This cascade of events causes allergic symptoms.
Therefore, option A is correct as it accurately describes the initial binding of allergen with IgE antibodies. Option B is incorrect as mast cells are activated, not deactivated. Option C is incorrect as the body is hypersensitive, not immunodeficient. Option D is incorrect as it is mast cells, not Helper T cells, that release histamine.