Nokea
What would be the conclusion?
- A. The water is safe for consumption
- B. The water quality is doubtful
- C. The water quality is extremely doubtful
- D. The water is polluted
Correct Answer: B
Rationale: Step-by-step rationale for choice B being correct:
1. The conclusion should be based on evidence or observations.
2. "Doubtful" suggests uncertainty, indicating lack of definitive safety.
3. Choice A is too absolute without considering potential risks.
4. Choice C uses extreme language without proper evidence.
5. Choice D is overly definitive without considering varying levels of contamination. Therefore, choice B is the most reasonable conclusion.
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A female who had been continuously taking antibiotics for an intestinal infection developed a complication manifested by inflammation of the oral mucosa and white deposit. Bacteriological study of the deposit samples revealed yeast fungi Candida albicans. Which of the following medications is indicated for the treatment of this complication?
- A. Fluconazole
- B. Biseptol
- C. Tetracycline
- D. Furazolidone
Correct Answer: A
Rationale: Rationale for Correct Answer (A: Fluconazole): Fluconazole is an antifungal medication used to treat yeast infections caused by Candida albicans. It targets the fungal cell membrane, disrupting its structure and function. This makes it an effective treatment for oral thrush, which is caused by Candida overgrowth in the oral mucosa. The continuous use of antibiotics can disrupt the normal balance of microorganisms in the body, leading to fungal overgrowth. Fluconazole specifically targets the yeast fungi without affecting bacteria, making it the appropriate choice for this complication.
Summary of Incorrect Choices:
B: Biseptol - Biseptol is an antibiotic that targets bacteria, not fungi like Candida albicans.
C: Tetracycline - Tetracycline is also an antibiotic that targets bacteria, not fungi.
D: Furazolidone - Furazolidone is an antibiotic primarily used for treating bacterial infections, not fungal infections like oral thrush caused by Candida
A 34-year-old male visited Tajikistan. After return, he complains of fever up to 40oC which occurs every second day and is accompanied by chills, sweating. Hepatosplenomegaly is present. Blood test results: RBC- 3x1012/l, b- 80 g/l, WBC- 4x109/l, eosinophils - 1%, stab neutrophils - 5%, segmented neutrophils - 60%, lymphocytes - 24%, monocytes - 10%, ESR - 25 mm/h. What is the provisional diagnosis?
- A. Malaria
- B. Infectious mononucleosis
- C. Sepsis
- D. Typhoid fever
Correct Answer: A
Rationale: The correct answer is A: Malaria. The patient's travel history to an endemic area like Tajikistan, along with symptoms of fever with chills, sweating, and hepatosplenomegaly, are classic for malaria. The blood test results show anemia (low RBC and hemoglobin levels), which can occur in malaria due to hemolysis. The presence of eosinophils and lymphocytes are not typical for malaria, but the overall clinical picture fits. Infectious mononucleosis (choice B) typically presents with sore throat, lymphadenopathy, and atypical lymphocytosis, which are not seen in this case. Sepsis (choice C) is characterized by systemic inflammatory response syndrome and organ dysfunction due to infection, which does not align with the symptoms and findings in the case. Typhoid fever (choice D) usually presents with gradual onset of sustained fever, abdominal pain, headache, and constipation, which are not present in this patient
Tuberculosis can be treated by means of combined chemotherapy that includes substances with different mechanisms of action. What antituberculous medication inhibits transcription of RNA into DNA in mycobacteria?
- A. Rifampicin
- B. Isoniazid
- C. Streptomycin
- D. Ethionamide
Correct Answer: A
Rationale: Rifampicin is the correct answer because it inhibits RNA transcription in mycobacteria by binding to the bacterial RNA polymerase. This prevents the synthesis of RNA, leading to the inhibition of protein production essential for bacterial growth.
Isoniazid inhibits mycolic acid synthesis, Streptomycin inhibits protein synthesis, and Ethionamide disrupts mycolic acid synthesis. These mechanisms are different from inhibiting RNA transcription, making them incorrect choices.
A scientist identifies a strand of RNA that can be directly used to code for important viral proteins during viral replication. What have they found?
- A. RNA major
- B. -RNA
- C. (+RNA)
- D. RNA minor
Correct Answer: C
Rationale: The correct answer is C: (+RNA). This indicates that the scientist found a positive-sense RNA strand that can be directly translated by host cell machinery to produce viral proteins. Positive-sense RNA can act as messenger RNA, allowing immediate protein synthesis during viral replication. Choice A (RNA major) and D (RNA minor) are not standard terms used to describe RNA strands in virology. Choice B (-RNA) indicates a negative-sense RNA strand, which requires transcription to form a complementary positive-sense strand before protein synthesis. Thus, the identification of a strand of RNA that directly codes for viral proteins aligns with the characteristics of a positive-sense RNA strand.
Which bacterial structure helps in the movement towards or away from chemical stimuli?
- A. Flagella
- B. Pili
- C. Capsule
- D. Fimbriae
Correct Answer: A
Rationale: Flagella are the correct answer because they are long, whip-like structures that aid in bacterial movement towards or away from chemical stimuli. They rotate like propellers, allowing the bacterium to navigate its environment. Pili are used for attachment, not movement. Capsules are involved in protection and adherence, not chemotaxis. Fimbriae help in attachment to surfaces, not in movement towards stimuli.