Pediatric Emergency Nursing PICO Questions Related

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when a female carrier of hemophilia marries a male who is free of the disease, the risk to their off spring for each pregnancy is what:

  • A. all female children will be carriers of hemophilia
  • B. half the male children will have the hemophilia
  • C. all male children will have the disease
  • D. half the female children will have hemophilia 125
Correct Answer: B

Rationale: Hemophilia is an X-linked recessive genetic disorder, meaning it is carried on the X chromosome. Females have two X chromosomes, while males have one X and one Y chromosome. In this scenario, the female carrier has one X chromosome with the hemophilia gene and one normal X chromosome. When she has children, she has a 50% chance of passing on the X chromosome with the hemophilia gene to her sons. Therefore, half the male children will inherit hemophilia, while half will not. Daughters, on the other hand, have a 50% chance of inheriting the X chromosome with the hemophilia gene but since it is a recessive disorder, they will be carriers of hemophilia rather than having the disease itself.