Drug Classification Quiz Related

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When blood glucose levels are difficult to control in type 2 diabetes some form of insulin may be added to the treatment regimen to control blood glucose and limit complication risks. Which of the following statements is accurate based on research?

  • A. Premixed insulin analogues are better at lowering HbA1C and have less risk for hypoglycemia
  • B. Premixed insulin analogues and the newer premixed insulins are associated with more weight gain than the oral antidiabetic agents
  • C. Newer premixed insulins are better at lowering HbA1C and postprandial glucose levels than long-acting insulins
  • D. Patients who are not controlled on oral agents and have postprandial hyperglycemia can have neutral protamine Hagedorn insulin added at bedtime
Correct Answer: D

Rationale: NPH at bedtime targets postprandial hyperglycemia in type 2 diabetes; premixed insulins vary in efficacy.