Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs Related

Review Roach's Introductory Clinical Pharmacology 11th Edition - Antihypertensive Drugs related questions and content

When educating a group of nursing students on the mechanism of action of angiotensin-converting enzyme inhibitor (ACEI) drugs, the instructor identifies which of the following as the action brought about by aldosterone?

  • A. Inhibits renin secretion
  • B. Causes sodium and water retention
  • C. Causes excess potassium retention
  • D. Promotes angiotensin I conversion
Correct Answer: B

Rationale: Aldosterone causes retention of sodium and water. This in turn causes a rise in blood pressure. ACEIs act by inhibiting the conversion of angiotensin I to angiotensin II. Aldosterone does not inhibit the release of renin and is not involved in the retention of potassium. Angiotensin-converting enzymes, and not aldosterone, are involved in the conversion of angiotensin I to angiotensin II.