Nokea
When prescribing Adderall (amphetamine and dextroamphetamine) to adults with ADHD the nurse practitioner will need to monitor:
- A. Blood pressure
- B. Blood glucose levels
- C. Urine ketone levels
- D. Liver function
Correct Answer: A
Rationale: Adderall increases blood pressure, requiring monitoring.
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This graph shows the concentration-dependent effects of norepinephrine on arterial blood pressure, both alone, and in the presence of a fixed concentration of Drug X. Which type of antagonist is Drug X?
- A. Silent
- B. Non-competitive
- C. Competitive
- D. Chemical
Correct Answer: B
Rationale: A non-competitive antagonist reduces the maximal response without shifting the potency (EC50), as indicated by the answer key, likely showing a decreased maximum on the graph.
A nurse is reviewing the health record of a client who asks about using Propranolol to treat hypertension. The nurse should recognize which of the following conditions is a contraindication for taking propranolol?
- A. Asthma
- B. Glaucoma
- C. Hypertension
- D. Tachycardia
Correct Answer: A
Rationale: Propranolol is contraindicated in asthma due to risk of bronchoconstriction.
The nurse is reviewing the history and physical examination of a client who will be receiving asparaginase (Elspar), an antineoplastic agent. The nurse consults with the registered nurse regarding the administration of the medication if which of the following is documented in the client's history?
- A. Pancreatitis
- B. Diabetes mellitus
- C. Myocardial infarction
- D. Chronic obstructive pulmonary disease
Correct Answer: A
Rationale: Asparaginase (Elspar) is contraindicated if hypersensitivity exists, in pancreatitis, or if the client has a history of pancreatitis. The medication impairs pancreatic function and pancreatic function tests should be performed before therapy begins and when a week or more has elapsed between administration of the doses. The client needs to be monitored for signs of pancreatitis, which include nausea, vomiting, and abdominal pain. The conditions noted in options 2, 3, and 4 are not contraindicated with this medication.
What is the entry of drugs into the plasma?
- A. Absorption
- B. Distribution
- C. Elimination
- D. Metabolism
Correct Answer: A
Rationale: Absorption is the process by which a drug enters the plasma from its administration site, the first step in pharmacokinetics.
A nurse is instructing a client who has a new prescription for Timolol how to insert eye drops. The nurse should instruct the client to press on which of the following areas to prevent systemic absorption of the medication?
- A. Bony orbit
- B. Nasolacrimal duct
- C. Conjunctival sac
- D. Outer canthus
Correct Answer: B
Rationale: Pressing the nasolacrimal duct prevents systemic absorption by blocking drainage into the nasal cavity.