Test Bank Pharmacology and the Nursing Process Related

Review Test Bank Pharmacology and the Nursing Process related questions and content

Which antiparkinsonian drug is associated with the on-off phenomenon and the wearing-off effect?

  • A. Amantadine
  • B. Levodopa
  • C. Benztropine
  • D. Pramixole
Correct Answer: B

Rationale: The correct answer is B: Levodopa. Levodopa is associated with the on-off phenomenon and wearing-off effect in Parkinson's disease treatment due to fluctuations in its effectiveness over time. The on-off phenomenon refers to sudden and unpredictable changes in motor function, while wearing-off effect occurs when the medication's effects diminish before the next dose. Amantadine (A) is not typically associated with these phenomena. Benztropine (C) is an anticholinergic used for tremors and rigidity. Pramixole (D) is a dopamine agonist that can cause dyskinesias but is not primarily linked to on-off or wearing-off effects.