Which bacteria are capable of producing exotoxins?
- A. Clostridium tetani
- B. Staphylococcus aureus
- C. Escherichia coli
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D: All of the above. Clostridium tetani, Staphylococcus aureus, and Escherichia coli are all capable of producing exotoxins. Exotoxins are proteins released by bacteria that can cause damage to the host. Clostridium tetani produces tetanospasmin, causing tetanus. Staphylococcus aureus produces toxins like enterotoxin and toxic shock syndrome toxin-1. Escherichia coli can produce Shiga toxin and heat-labile toxin. Therefore, all three bacteria listed can produce exotoxins, making choice D the correct answer. Choices A, B, and C are incorrect as they do not encompass all the bacteria capable of producing exotoxins.
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The most rapid rate of drug absorption is achieved by __________ administration.
- A. on the skin
- B. intravenous
- C. intramuscular
- D. sublingual
Correct Answer: B
Rationale: The correct answer is B: intravenous administration. This route bypasses the first-pass metabolism, allowing the drug to directly enter the bloodstream for immediate distribution. In contrast, on the skin (A) and sublingual (D) routes have slower absorption rates due to barriers like skin layers or mucous membranes. Intramuscular (C) absorption is slower than intravenous due to slower perfusion rates in muscle tissues. Overall, intravenous administration provides the fastest and most direct route for drug absorption, making it the most rapid method.
Which bacteria produce a toxin that inhibits protein synthesis?
- A. Shigella dysenteriae
- B. Clostridium botulinum
- C. Streptococcus pneumoniae
- D. Mycobacterium tuberculosis
Correct Answer: A
Rationale: The correct answer is A: Shigella dysenteriae. This bacteria produces the Shiga toxin, which inhibits protein synthesis by interfering with the ribosomes. Shigella dysenteriae causes severe gastrointestinal illness. The other choices, B: Clostridium botulinum, produces a neurotoxin that blocks neurotransmitter release. C: Streptococcus pneumoniae causes pneumonia and other respiratory infections. D: Mycobacterium tuberculosis causes tuberculosis by infecting the lungs. Thus, based on the toxin production and mode of action, Shigella dysenteriae is the correct answer.
An example of selective media is:
- A. McConkey agar
- B. Bordet Gengou agar
- C. Peptone water
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A: McConkey agar. Selective media selectively inhibit the growth of certain organisms while allowing others to grow. McConkey agar contains crystal violet and bile salts that inhibit the growth of Gram-positive bacteria, making it selective for Gram-negative bacteria. Choices B and C are not selective media, as they do not specifically inhibit the growth of certain types of bacteria. Choice D is incorrect as McConkey agar is indeed an example of selective media.
Gram-negative rods producing red colonies on Endo agar were isolated from a fecal sample. The bacteria were lactose-fermenting. What microorganism is likely responsible?
- A. Escherichia coli
- B. Salmonella
- C. Shigella
- D. Proteus
Correct Answer: A
Rationale: The correct answer is A: Escherichia coli. E. coli is a Gram-negative rod that ferments lactose, leading to red colonies on Endo agar. This bacterium is commonly found in the human gut and is known for its ability to ferment lactose. Salmonella and Shigella are also Gram-negative rods but do not ferment lactose, so they would not produce red colonies on Endo agar. Proteus is a Gram-negative rod that is not known for its lactose-fermenting ability and would not produce red colonies on Endo agar. Therefore, based on the characteristics provided, E. coli is the most likely microorganism responsible for the red colonies on Endo agar.
In the South and Central America there can be found a species of trypanosomes that is the causative agent of Chagas disease. What animal is the infection carrier specific to this disease?
- A. Triatomine bug
- B. Mosquito
- C. Tsetse fly
- D. Cockroach
Correct Answer: A
Rationale: The correct answer is A: Triatomine bug. Triatomine bugs, also known as "kissing bugs," are the specific carrier of the trypanosomes that cause Chagas disease. These bugs transmit the parasite through their feces, which contain the infectious forms of the trypanosomes. When the bug bites a human or animal, it defecates near the bite wound, allowing the parasites to enter the bloodstream through the broken skin. Mosquitoes (B) transmit diseases like malaria and dengue fever, not Chagas disease. Tsetse flies (C) are known for transmitting African trypanosomiasis (sleeping sickness), not Chagas disease. Cockroaches (D) are not known to transmit Chagas disease.